Improvement in Scalp Dermatomyositis with Platelet-Rich Plasma- Open access journals

Juniper Publishers- JOJ Dermatology & Cosmetics


Authored by Hosking AM


Dermatomyositis (DM) is an inflammatory myopathy with hallmark cutaneous findings, including heliotrope rash, Gottron’s papules, as well as photodistributed erythema and/or poikiloderma. Scalp DM (SDM) presents as erythematous plaques with overlying scale, associated with severe burning pruritus. Due to inflammation, it may also present with non-scarring alopecia. First-line treatment for SDM includes intralesional corticosteroids; however, to date, no therapy has proven effective. Platelet-rich plasma (PRP) is an emerging treatment modality for a variety of disease entities including arthritis, oral surgery, and skin rejuvenation. Recent reports demonstrate PRP may have a promising role in hair regrowth. Herein, we report a case of refractory SDM with significant clinical improvement after treatment with subdermal PRP injections of the scalp. We also used optical coherence tomography (OCT) as a non-invasive imaging methodology to longitudinally monitor hair growth over the 18-week PRP treatment interval.


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