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Showing posts with the label Chemical peels

Bulbous and Globose-Merkel Cell Carcinoma

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    Open A ccess  Journal of  JOJ Dermatology & Cosmetics  Editorial Merkel cell carcinoma is an infrequently discerned, aggressive, primary cutaneous carcinoma of neuroendocrine origin. Additionally designated as trabecular carcinoma and initially scripted by Toker in 1972, tumefaction simulates numerous benign and malignant cutaneous lesions. Localized disease is common, followed by regional lymph node or distant metastasis. Spontaneous regression of disease is exceptional. Disease-associated mortality is significant [1,2]. Primary cutaneous Merkel cell carcinoma can be segregated from metastatic cutaneous neuroendocrine carcinoma with pertinent clinical and histological examination along with immunohistochemistry. Majority of neoplasms may be engendered due to infection with Merkel cell polyomavirus. Few instances emerge due to ultraviolet radiation induced activation of diverse onco-genetic pathways [1,2]. Generally, elderly Caucasian population >70 y...

Efficacy of Combined Low-Dose Hormonal Contraceptives in the Treatment of Acne Vulgaris-A Randomized Control Trial Study

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    Open A ccess  Journal of  JOJ Dermatology & Cosmetics   Introduction Acne vulgaris is a skin condition that affects a high number of teenagers and young adults. The pilosebaceous unit is impacted by this multifactorial inflammatory disorder. The understanding of acne pathogenesis is constantly changing. Sebum production, follicular hyper keratinization, complex inflammatory processes, and Propionibacterium acnes microbiological colonization are significant pathogenic elements that contribute to the onset of acne. Acne vulgaris has a substantial physical and psychological morbidity, including low self-esteem, poor self-image, scars, and depression. According to estimates, 12.6% of all dermatological treatment costs in the world go toward treating acne [1]. Due to this and referring the effects of acne and psychological affects to the adolescent it is quite important to focus on new research for efficacity in acne treatment. Aim of the study:  To veri...

REGENERAGE® Cream Anti-aging Effect in Women

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  Juniper Publishers- JOJ Dermatology & Cosmetics Summary Introduction:  The skin aging, in addition to the general guideline of the whole organism, is negatively influenced by various internal and external factors that can accelerate and modify it. There are several anti-aging therapies, including those for topical use with greater acceptance among users. Bioquantine® is an innovative product with regenerative properties that has been added to REGENERAGE® cream. Objective:  To evaluate the REGENERAGE® cream anti-aging effect in 12 women. Material and Methods:  Exploratory clinical trial, randomized, double-blind, placebo-controlled parallel group. Ten healthy volunteers with a diagnosis of facial photo-aging were included. They were randomly assigned to the REGENERAGE® cream in half of the face and placebo cream in the other; The study products were applied every day in the morning and evening, for 12 weeks. Baseline evaluations were carried out in week 6 and 12...

Importance of Psychiatric Evaluation and Patient Selection in the Field of Cosmetic Dermatology

    Juniper Publishers- JOJ Dermatology & Cosmetics Introduction Cosmetics is an ever-increasing component of every-day practice for dermatologists. However, as elective procedures such as neuromodulator injections, dermal fillers, and body contouring have pushed their way into most dermatology practices, little objective research has been done to identify ideal patients to undergo these procedures. It is the opinion of these authors that objective studies to evaluate the pre and post procedural psychologic well-being are essential to identify patients who may have an underlying and undisclosed psychiatric illness that is contributing to their decision-making process. This issue is further complicated by the plethora of cosmetic day-spas that offer these services without physician oversite or ethical obligation to responsibly select candidates. One example regarding the importance of patient selection is exemplified by patients with body-dysmorphic disorder (BDD) - a condi...