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Showing posts from February, 2022

Propranolol for the Treatment of Hemangiomatosis with Hepatic Lesions: Case Report with Great Response

  Juniper Publishers- JOJ Dermatology & Cosmetics Abstract We present a case of a 2 months-old male nursling with neonatal hemangiomatosis with skin and hepatic, showing great response with systemic propranolol, with good acceptance, without side effects, after a 9 months follow-up. Keywords: Hemangiomatosis, Disseminated; Hemangioma/drug therapy; Liver Neoplasms/drug therapy; Propranolol/therapeutic use Abbreviations:  IH: Infantile Hemangioma; ISSVA: International Society for the Study of Vascular Anomalies; NH: Neonatal Hemangiomatosis; BNH: Benign Neonatal Hemangiomatosis; VEGF: Vascular Growth Endothelial Factor; DNH: Diffuse Neonatal Hemangiomathosis; FGF: Fibroblast Growth Factor Introduction Vascular tumors are vasculature neoplasms that present endothelial cell proliferation. Infantile hemangioma (IH) is a proliferation of endothelial cells, that develop during the first 12-18 months of life, and then involute1. The lesions may be present at birth as a precursor lesion, bu

Single Plaque-Type Chromoblastomycosis: Great and Sustained Response with Itraconazole Plus Cryosurgery

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                                         Juniper Publishers- JOJ Dermatology & Cosmetics Abstract We present a 72-years-old male patient, resident in a urban area, with a chronic cutaneous ulcer on the left forearm, diagnosed with chromoblastomycosis, treated with a combination therapy of oral itraconazole and cryocirurgery, with 6-months follow up after treatment. Keywords: Black Fungi; Chromoblastomycosis; Chromomycosis; Melanized Fungi; Muriform (Sclerotic) Cells Introduction The Chromoblastomycosis (CBM) is a chronic fungal infection caused by the traumatic implantation of demeaceous fungi of the Herpotrichiellaceae family on the skin and subcutaneous cellular tissue [1-3]. These fungi are more common in tropical and subtropical areas, and can be found in the soil, in vegetation and decomposing wood [1,2]. It is more common in male rural workers, lumbermen or sellers of agricultural products [4]. Brazil is the second country in number of cases, being found throughout its entire