Palmoplantar Pustulosis with Subungual Pustules Treated with Arotinoid Ethyl Ester
Juniper Publishers- JOJ Dermatology & Cosmetics Abstract A 43-year-old Chinese man developed crops of pustules on soles for 7 months and subungual pustules for 6 months. Biopsy on the sole lesion revealed intraepidermal unilocular pustules filled with bulk of neutrophils. This case proved to be palmoplantar pustulosis with nail involvement. After 28-week treatment with arotinoid ethyl ester, all plantar and subungual lesions cleared completely. The treatment of PPP is challenge; especially for the subungual pustules are rare and difficult to be diagnosed and treated. Herein we report the case and effective therapy with literature review. Keywords: Arotinoid ethyl ester Palmoplantar pustulosis Subungual pustules Introduction Palmoplantar pustulosis (PPP), synonymously as localized pustular psoriasis, is characterized by recurrent sterile pustules bilaterally and symmetrically on palms and soles. Nail changes in PPP are rare and difficult to be diagnosed and treate...