Open A ccess Journal of JOJ Dermatology & Cosmetics Introduction Acne vulgaris is a skin condition that affects a high number of teenagers and young adults. The pilosebaceous unit is impacted by this multifactorial inflammatory disorder. The understanding of acne pathogenesis is constantly changing. Sebum production, follicular hyper keratinization, complex inflammatory processes, and Propionibacterium acnes microbiological colonization are significant pathogenic elements that contribute to the onset of acne. Acne vulgaris has a substantial physical and psychological morbidity, including low self-esteem, poor self-image, scars, and depression. According to estimates, 12.6% of all dermatological treatment costs in the world go toward treating acne [1]. Due to this and referring the effects of acne and psychological affects to the adolescent it is quite important to focus on new research for efficacity in acne treatment. Aim of the study: To verify the effectiveness of low-d
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