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Showing posts from July, 2022

Treatment of Dystrophic Epidermolysis Bullosa with Transforming Powder Dressing

Abstract Dystrophic epidermolysis bullosa is a disabling blistering disorder, characterized by significant pain, extensive nursing care, and difficult wound healing. The following case presents a transforming powder dressing which provided pain reduction, atraumatic and reduced dressing changes, as well as improved healing in one patient. Read More About this article :  https://juniperpublishers.com/jojdc/JOJDC.MS.ID.555610.php Read More Juniper Publishers Google Scholar Article:  https://scholar.google.com/citations?view_op=view_citation&hl=en&user=hzQkAiQAAAAJ&citation_for_view=hzQkAiQAAAAJ:dhFuZR0502QC

Induced Auto-Regeneration with Adipose Tissue in Humans – Beyond Frontiers of Healing

  Opinion The search for regeneration of the face and other structures of the human body has undergone several attempts, based on complex surgical techniques with the use of transplantation of fragments or limbs removed from donors, followed by the administration of immunosuppressive drugs for the rest of the patient’s life. The results of these face transplants are far from ideal and the degree of dissatisfaction in these patients is very high, leading to cases of severe depression, treatment abandonment and even suicide. In addition to technical problems such as recovery of facial mobility, transplantation of an external anatomical unit differs greatly from transplantation of an internal organ, as its immune behavior is very different. The skin represents the interface between the internal environment of our body and the external environment, therefore it has a rich defense system specialized in responding to all sorts of invaders, which makes it extremely antigenic. For this reason,

Do Normal Human Epidermal Keratinocytes Require a Priming Step to Activate the NLRP3 Inflammasomes to Exogenous Threats?

  In recent work examining the expression of inflammas Come-induced release of active Caspase-1 on Normal Human Epidermal Keratinocytes (NHEK), it was noted that two exogenous threats, UVB radiation and ATP were effective at activating the NLRP inflammasomes and inducing the release of significant quantities of active Caspase-1 [1]. It is generally thought that activation of the NLRP inflammasomes is a two-step process requiring: 1) activation of the NLRP inflammasome by signaling from the Toll-Like Receptors (TLR), and 2) creation of the inflammasome proteins after transcription via NF-ƙβ nuclear signaling, assembly of the inflammasome complex and subsequent activation of Caspase-1 upon binding to the ASC binding domain of the inflammasome [2]. Active Caspase-1 then begins to cleave inert cytokines such as IL-1β and IL-18 and causes the activation of gasdermin D, a transmembrane pore-forming protein, that initiates a form of cell death called pyroptosis that commences the downstream p

A Novel Methodology for Correction of Cosmetic Problems via Secondary Eyebrow Transplantation - Juniper Publishers

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    Open A ccess  Journal of  JOJ Dermatology & Cosmetics  A Novel Methodology for Correction of Cosmetic Problems via Secondary Eyebrow Transplantation - Juniper Publishers Authored by Yi Jung Lin Abstract Eyebrows create a very imperative and noticeable feature of the face. With increasing information, eyebrow transplant has become a prevalent technique. Though it is a small area still requires a lot of precision, knowledge and aesthetic skill regarding anatomy, designing of brows, extraction and implantation technique. In this paper, we performed many cases of eyebrow reconstuction including revision by our own implanter. The cases analyzed in this paper were corrected only by transplantation of occipical donor hair without laser hair removal nor tattoos. This article gives a comprehensive view regarding how to correct previously unsatisfactory eyebrow transplant with special emphasis on several points as hair follicle density, eyebrow shape, entire or partially re